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239 In an uncontrolled trial that included 15 women with fibromyalgia, seven of whom had also been diagnosed with chronic fatigue syndrome, treatment with a synbiotic (probiotic/prebiotic combination) for 30 days decreased stress, anxiety, and depression, improved quality of life, and reduced IL-8 levels

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In another study, an 84-week open-label trial with about 800 participants, people taking CagriSema had an average of 23% weight loss versus about 25 to 26% for tirzepatide (Zepbound) at the highest dose