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The role of Nrf2 in the transcriptional regulation of these scavenger receptors and cholesterol efflux transporters has been established

Secretin, for example, is an expensive intravenous drug that was studied in seven randomized controlled trials before all the evidence was systematically reviewed and it was conclusively determined to be ineffective [10]

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94,95 Furthermore, tumor cells have more abundant microvilli on their cell surface in comparison with normal cells, and the increased overall surface area of tumor cells allows a greater number of AMP molecules to interact with the surface of cancer cells, thereby promoting AMP-mediated cytotoxicity