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Description

It's typically a positive sign, though understandably concerning

To ensure sink conditions during the entire experiment, the volume of the receiver phase (10 mL) was set to be more than 10 times the maximum expected amount of permeated drug, based on preliminary solubility data

Colchicine also disrupts the activation of inflammasome, suppressing activation of caspase-1 and subsequent release of IL-1 and IL-18 (Montealegre-Gmez et al., 2020)