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Diabetes mellitus and diabetes-associated vascular disease

Increased expression of USP25 in AKI affects PKM2 (M2 isoform of pyruvate kinase, muscle), a crucial enzyme for glycolysis, which in turn causes kidney damage in AKI[105]

Transmembrane reductase of ferricyanide (TMR) expresses the existence of an erythrocyte transmembrane redox system responsible for, among others, recycling antioxidants (Hatherill et al., 1991