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Thus, 38 subjects (20 men, 18 women) were retained (Fig 1)

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If left unaddressed, a deficiency can result in severe complications, including irreversible nerve damage or memory impairment, making early diagnosis and ongoing treatment essential

However, the specific impact of disrupting this pathway via myeloid-specific HIF-1 deletion on macrophage function and the overall bone regeneration process remains an open and critical question