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Understanding the individual effects of SHBG and factors that may influence its levels is crucial when considering SHBG as a potential therapeutic for metabolic dysfunction or type 2 diabetes, since changes in its levels would also modulate androgen and oestrogen bioavailability, while endogenous factors may modify its levels and influence the therapeutic outcomes

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About the Study New research findings published in Nature Medicine come from an analysis of the large-scale COSMOS (COcoa Supplement and Multivitamin Outcomes Study) clinical trial

It is a prime example of typical neuropathic pain which in many cases contributes to a significant reduction in the patients quality of life