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In cancer cells, genetic and epigenetic dysregulation of MYC expression and the loss of checkpoint components unleash the ability of MYC to promote cell growth, eventually leading to malignant transformation 176

Slattery JT, Nelson SD, Thummel KE

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Proc Jpn Acad (1987) 63:2313.10.2183/pjab.63.231 110 DanforsTvon KnorringALHartvigPLangstromBMoulderRStrombergBet alTetrahydrobiopterin in the treatment of children with autistic disorder: a double-blind placebo-controlled crossover study