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While significant MF classifiers includes: catalytic activity (GO:0003824), ion binding (GO:0043167), nucleotide binding (GO:0000166), ribonucleotide binding (GO:0032553), ATP binding (GO:0005524), protein binding (GO:0005515), ligase activity (GO:0016874), ATPase activity (GO:0016887), ion channel activity (GO:0005216), cation channel activity (GO:0005261), aminoacyl-tRNA ligase activity (GO:0004812), carbon-carbon lyase activity (GO:0016830), carboxy-lyase activity (GO:0016831), aminopeptidase activity (GO:0004177), sucrose synthase activity (GO:0016157), 4-alpha-glucanotransferase activity (GO:0004134), beta-maltose 4-alpha-glucanotransferase activity (GO:0102500)