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doi: 10.1016/j.immuni.2022.03.005 26 LeeJLeeSHShinNJeongMKimMSKimMJet al

Characteristic changes in patients with metabolic disorders include a decrease in serum high-density lipoprotein (HDL) or an increase in serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), fasting plasma glucose (FPG), and homeostasis model assessment-insulin resistance (HOMA-IR)

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In combination, more effort needs to be made to include correctly matched controls. Referring to the 25% of individuals with ME/CFS who are house or bedbound It is important to make research more available for this percentage of ME/CFS cases, since they are the most severely affected by the disease and these severe cases are rarely studied