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doi: 10.1038/s41598-019-40093-9

Studies reveal saffron improves antidepressant-caused sexual dysfunction [48]

In addition, combining treatments may provide a better safety profile given that lower doses of each drug when used together may achieve better weight loss than higher doses of a single agent (see Figure 1 below)

While the exact location of the neurological injury has yet to be identified since MRI (0.5 T) assessments conducted in 1993 on 2 konzo-affected individuals reported no pathological findings, the phenotypic presentation of various severities (Stages 13) of hyperreflexia and non-spastic paraparesis suggests damage of motor neurons and corresponding brain regions