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[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

Moran et al., 2000

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Afterward, a mixture of methanol-saturated petroleum ether and petroleum ether-saturated methanol (1:1, by volume) was sequentially added to the total fat, followed by sequential addition of petroleum ether-saturated methanol and methanol-saturated petroleum ether mixture (6:1, by volume) after shaking and homogenization