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SUMO1 deficiency exacerbates neurological and cardiac dysfunction after intracerebral hemorrhage in aged mice

Because GH and IGF-1 promote protein synthesis and lipolysis, these hormonal changes provide a plausible mechanistic basis for modest increases in lean body mass, improved recovery and support for fat loss seen in clinical and observational contexts, but robust controlled trials explicitly measuring those endpoints are still lacking

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For a broader look at what B12 does beyond energy including its role in nerves, methylation, and brain health see our complete vitamin B12 benefits guide