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Laboratory assessment of sudden sensorineural hearing loss: A case-control study

SCF/-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

However, clinical translation is hindered by low oral bioavailability, limited BBB permeability, and inconsistent pharmacokinetics

Beyond targeting ionotropic receptors, several studies have also reported the alleviation of core ASD symptoms through modulation of mGlu receptor activity, particularly mGlu4 and mGlu5 receptors [54,55,56]