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Although ROS generation may not be an essential factor for aging (Lpez-Otn et al., 2013), they are more likely to exacerbate age-related diseases progression via oxidative damage and interaction with mitochondria (Dias et al., 2013)

Similar content being viewed by others Introduction Iron is an important trace element for living organisms [1] as it participates in a range of metabolic processes, such as oxygen transport, energy metabolism, nucleotide synthesis, and electron transport [2]

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(4) Dose titration: Therapy is typically initiated at low doses and titrated gradually to achieve optimal symptom control while minimizing adverse effects, with the goal of identifying the lowest effective daily dose