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Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

An additional feature of the mammalian mechanism is the presence of a selenocysteine residue at the C-terminal end of the protein which is required for catalytic activity

Though G6PD is found in the cytoplasm of all mammals cells, its deficiency is more evident in the red blood cells probably because these cells live without nucleus for a long time and because they contain proteases that degrade the mutant enzyme in major degree than other proteases in other tissues 1

In the biochemical process involving oxygen, i.e., during oxidation, many highly unstable reactive molecules called free radicals are produced