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In keloids, it disrupts the FOXO4-p53 interaction, inducing apoptosis in senescent fibroblasts and reducing pro-inflammatory and mesenchymal fibroblast subpopulations

Gurpilhares, D

314 Another key player in the mitochondria-ROS-mTORC1 axis is SESTRIN2, which regulates mitochondrial respiration 315 and exhibits antioxidant properties that mitigate ROS levels