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Amino acid transporter LAT3 is required for podocyte development and function

Treatment schedule consists of two initial PE-A5% sessions on consecutive days followed by every other day PE-A5% (minimum 4, maximum 9 PE-A5%)

Conclusion: The hydrophobic secondary BAs are the major factors that induce PSC via the liver-large intestine axis by promoting periductal fibrosis and large intestinal leakage