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As a consequence of these challenges to utilising human tissue in cataract research, animal models have been used to investigate the underlying mechanisms of cataract formation (26) following a range of cataractous insults

Recent findings have even shown that functional abnormalities of the BBB represent additional pathological changes associated with MS (254)

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Tirzepatide the approved label starts at 2.5 mg once weekly and escalates in 2.5 mg steps at intervals of at least four weeks, to a maintenance dose of up to 15 mg once weekly