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Muscle tissue is often preferred for biopsy due to its high energy demand, making it particularly susceptible to OXPHOS dysfunction

enterica serovar Typhimurium, invasive enteric pathogen, represses serine synthesis in macrophages in vitro, via a type III secretion system effector protein called SopE2, leading to the accumulation of 2-PG, 3-PG and phosphoenolpyruvate, which serve as carbon sources 141 (Fig