b12 injectable complex Vitamin B Injections vitamin solution for use in the relief of B vitamin deficiencies and to provide supplemental nutritional vitamins to cattle Methylcobalamin Injection (Vitamin B12) |

B12 injections are generally considered safe and well-tolerated

A commenter supported CMS' proposal to utilize this measure as specified with anonymous administration, supplying potential data collection options to address the anonymity requirement while emphasizing that the measure is evidence-based, has been tested to show moderate reliability, and has been endorsed by a CBE for the hospital outpatient department setting and has been adopted for the Hospital OQR Program

"Pernicious Anemia", StatPearls , Treasure Island (FL): StatPearls Publishing, PMID 31082033, retrieved July 15, 2025 "Vitamin B12 or folate deficiency anaemia Diagnosis"

They are also effective for managing painful periods, general muscle spasms, and symptoms of fibromyalgia