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TSHR CAAR T cells, co-cultured in vitro with anti-TSHR B cells that were transduced by lentivirus, exhibited significant increases in IFN, IL-2, and TNF levels within 24 hours, effectively eliminating autoreactive anti-TSHR B cells without affecting other B cell populations

Plate [A] Control: normal mammary gland histoarchitecture with fat globule [FG], showing normal alveolar milk lumen [AML], and alveolar epithelium [AE] with normal epithelial cells

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When cortisol rebinds to the cavity, electron transfer via PB nanoparticles is inhibited, resulting in a signal-off response observed in DPV measurements, with the current decreasing in a concentration-dependent manner [Figure 8E]