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Conclusion In conclusion, our observations support the concept that an HFD alters the output component of the circadian rhythm of the MGs, rather than the core clock machinery (Figure 7)

Machine learning approaches, including random forests, support vector machines, and deep learning algorithms, have been successfully applied to multi-omics data for biomarker discovery and outcome prediction [74,75,76]

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10.1371/journal.pone.0167124 39 FlowersN.HartleyL.TodkillD.StrangesS.ReesK