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In a bleomycin-induced rat model of pulmonary fibrosis, intravenous infusion of bone marrow MSCs (BMSCs) markedly reduced collagen deposition and hydroxyproline content in lung tissue via activation of the Nrf2/ARE signaling pathway, while increasing SOD activity and decreasing MDA levels, thereby effectively attenuating oxidative stress and tissue fibrosis [90]

Br J Haematol (2004) 124(5):6107

At the genus level, the staphylococcal load increased in CHP, and the Actinomyces and Veillonella loads increased in IPF

demonstrated that in androgen-dependent and -independent prostate tumor cells as well as in human prostate cancer specimens, the overexpression and the increased activity of CACT is a hallmark of prostate cancer 22