1000mg l carnitine L-Carnitine 1000 Acetyl L-Carnitine HCL, 60 Capsules

Introduction -thalassemia is the most common inherited disease, characterized by decreased or absent -globin chain synthesis and hemoglobin A production ( The incidence of myocardial iron overload in transfusion-dependent -thalassemia patients has increased from 11.4%15.1% in early studies to 26.1%36.7% in recent studies ( As iron loading progresses, the capacity of transferrin to bind and detoxify iron is eventually exceeded, leading to non-transferrin-bound iron in plasma, which promotes oxidative stress, mitochondrial dysfunction, and ferroptosis ( Mechanisms of myocardial injury caused by iron overload Studies have shown that iron myocardial overload causes myocardial dysfunction

Post-transcriptional regulation also contributes to CYP51A1 repression

A 5mg TB-500 vial reconstituted with 2mL produces 2.5mg/mL

Acknowledgements This work was supported by the project SV2114-2024, project MH CZDRO (UHHK, 00179906) and CZ.10.03.01/00/22_003/0000048