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In aged rhesus macaques ( Macaca mulatta ) supplemented with taurine, notable improvements were observed: increased bone density, reduced fasting blood glucose levels, and lowered serum concentrations of liver damage markers AST and ALT

were the first to hypothesize that reducing NLRP3 may extend HS by delaying multiple age-related degenerative changes in the periphery and the brain

These proteins are essential for regulating the paracellular transport thereby controlling the selective passage of ions, solutes, and water between intestinal epithelial cells (Van Itallie and Anderson, 2014), maintaining cell polarity and facilitating cell differentiation and proliferation (Farkas et al., 2012)