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doi: 10.1016/j.arr.2016.05.012 80

& Bickel, S

Ruvolo P, Ma H, Ruvolo V, Mu H, Shober W, Yasuhiro T, Yoshizawa T, Gallardo M, Zhang X, Khoury JD, Cortex JE, Andreeff M , Post SM

Conversely, in cells where NADPH-consuming reactions are active (e.g., fatty acid synthesis, antioxidant defense), the cytosolic concentration of NADPH decreases, while NADP + increases