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Naive B cells may become fewer in number and less able to react to antigens if ferroptosis is induced in them

Antineoplastic agents such as cisplatin (Li et al., 2016a), methotrexate (Erboga et al., 2015), doxorubicin (Heeba and Mahmoud, 2016), and cyclophosphamide may cause side effects in clinical treatment due to dose-related nephrotoxicity