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In addition, curcumin is known as a generally recognized as safe substance ( Challenges and limitations Despite its promising therapeutic potential, curcumin exhibits poor aqueous solubility (11 ng/mL), chemical instability at neutral to alkaline pH, and low oral bioavailability due to rapid hepatic metabolism and systemic elimination

Also, many goat farmers give BoSe injections to adult and newborn goats as part of their regular goat health care

MOF-mediated acetylation enhances NRF2 nuclear retention and downstream gene transcription, playing a critical role in antioxidant responses and drug resistance, and regulating tumor growth and resistance through an NRF2-dependent mechanism [58]

In a study conducted by Anqi Zhang et al., T-cell-mediated RA was successfully induced in SKG mice through a zymosan A injection [105]