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We elected not to propose use of a historical lookback approach (under options 1 and 2) because ASP units are often missing, negative, or equal to zero for the most recent calendar quarter and/or over several quarters in a four-quarter lookback period, and so including additional quarters may not necessarily yield additional data that could be used to apportion inflation rebate amounts (and could complicate the calculation of an average by introducing a mix of missing units, negative units, or units equal to zero, and positive units within a single NDC)

Some experience pain or irritation at the injection site

If a single strand of hair starts out brown (or red or black or blond), it is never going to change its color (unless you color your hair)

Many consumers prefer options that contain only water and carbon dioxide