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197 This strategy, however, not only fails to guarantee uniform drug absorption but also exacerbates systemic toxicity

doi: 10.1038/nature05859 14 WangXFangXWangF

In normal human lung parenchyma, repair processes in response to mechanical injury are associated with increased TGF signaling, while a decrease in expression has been observed for TGF-related genes with worsening lung function in patients with COPD [25, 45]