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As for the effect of this oxidative stress on fertility, several studies have shown that between 30 and 80% of male sterility problems are caused by the presence of ROS in semen

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24 Stress-induced autophagy and its dual role in cardiac remodeling Autophagy is dynamically activated in response to hemodynamic stress

Loss of PON1 also reduces HDLs ability to prevent oxidation of its own lipids and proteins, which has been reported in metabolic syndrome as oxidation of apoA-I impairs HDLs RCT and anti-inflammatory functions (865)