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LEfSe is known to reduce false positives and can highlight biological consistency across subclasses, while the KruskalWallis test used alone can achieve a lower false-negative rate compared to LEfSe 38

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It promotes new blood vessel formation, stimulates keratinocyte and fibroblast migration into wound sites, and modulates the inflammatory response by reducing local levels of inflammatory cytokines all critical to healing after oral surgical procedures

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