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Interestingly, studies also suggests that sulfate and glucuronide metabolites in the intestine and phenolic compounds such as hydroxytyrosol and Tryrosol can also inhibits NF-B-induced iNOS gene expression by activating Nrf-2 signaling (205, 206)

To determine the structure of NC after the ligand exchange, we performed molecular modeling based on the combination of density functional theory (DFT) and semi-empirical quantum method PM7 approach (see Computational details)

FasL expression on human nucleus pulposus cells contributes to the immune privilege of intervertebral disc by interacting with immunocytes

These outcomes are particularly important because managing both blood sugar and weight can reduce the risk of diabetes-related complications such as cardiovascular disease and kidney damage