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Glutathione keeps them in check, protecting your mitochondria, DNA, and cell membranes so your body runs like the well-oiled, oxygen-fuelled machine its meant to be

In brief, 50-100 mg leaf samples were frozen in liquid nitrogen, and ground with 1 mL Extraction Buffer [50 mM EPPS buffer, pH 8.0, containing 1 mM EDTA, 10 mM DTT, 0.1% Triton X-100 [v/v], 0.5% polyvinylpyrrolidone, and 1x SigmaFAST Protease Inhibitor Cocktail, EDTA Free (Sigma)] on ice using 2 mL glass-to-glass homogenizer

Small amounts of unmetabolized quercetin are metabolized in the hepatic and intestinal circuits and enter the systemic circulation or are excreted in the bile

Notably, Fe and Zn in these patients remain normal, suggesting that SLC39A14 deletion specifically affects Mn (Tuschl et al., 2016