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These include domoic acid, the cause of amnesiac shellfish poisoning, from the alga Pseudo-nitzschia (Grant et al., 2010), - N -oxalylamino-L-alanine (BOAA), the cause of lathyrism, from the plant Lathyrus sativus (Ludolph and Spencer, 1995) and possibly - N -methylamino-L-alanine (BMAA), a postulated cause of Guamian amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC), from the cycad Cycas circinalis (Karamyan and Speth, 2008)

Chronic ketamine exposure in rodent models (50 mg/kg daily for 8 weeks) leads to significant activation of microglial cells and elevated expression of proinflammatory cytokines, such as IL-6 and IL-1, which correlate with hippocampal neuronal damage (Yin et al., 2022)

pseudomallei is resistant to the majority of antibiotics