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Description

This step is usually quicker than the initial application, but the success rate is low

Janocha, A

In preclinical models of cerebral ischemia, GLPs significantly diminish cerebral infarct volume and attenuate neuronal cell death by modulating the mitochondrial apoptotic pathwayspecifically, by upregulating the anti-apoptotic protein Bcl-2, downregulating the pro-apoptotic factor Bax, and suppressing the activation of executioner caspases (caspase) (Liu X