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In prostate cancer [68] and lung cancer [69], SLC38A2 is markedly expressed, thereby playing a significant role in tumorigenesis

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Nat Commun 14(1):7791 Zhao Z, Chen Q, Qiao X, Wang J, Ali ZTA, Li J et al (2025) Sulforaphane in cancer precision medicine: from biosynthetic origins to multiscale mechanisms and clinical translation

Orally ingested aspartame components are immediately absorbed from the lumen and reach the portal blood in a manner similar to that of amino acids arising from dietary protein or polysaccharides.4,5 Their concentrations are found increased in the blood stream.6 This sweetener and its metabolic breakdown products (phenylalanine, aspartic acid and methanol) have been a matter of extensive investigation for more than 20 years, including experimental animal studies