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Quantification was done in at least 10 fields for each condition and the proportion of dead cells was calculated as a percentage of total cells expressing the WT or WD-associated variants

The pharmacological targeting of Rev-erb using SR9009 induced a significant reduction in collagen deposition, hydroxyproline content and the expression of fibrosis-related genes Col11 and TGF-1 in the CDA-HFD mouse model

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Glutamine uptake images were measured using the rapid acquisition with relaxation enhancement (RARE) protocol