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Doseresponse curves were generated at equilibrium (10 min) and EC 50 values were calculated from this

In vitro , CVC could transcriptionally suppress crucial profibrotic genes ( Xaf1 , Slfn4 , Slfn8, Ifi213 , and Il1b ) in macrophages by inactivating the STAT1/NFkB/ERK signaling pathways