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Free iron can be used in the Fenton reaction with H 2 O 2 to generate OH consequently contributing to further enhancement of oxidative stress, lipid peroxidation events, and ovarian damage [21, 59]

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Nutritional psychiatry: where to next

Thus, future research should explore the potential of metformin in preventing IIRI in patients with early risk factors, and develop combinatory treatments that offer both immediate and sustained protection against IIRI