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The proteins responsible for that transformation were introduced in human cells in the lab and started working in a way similar to how the tun state works

Lyophilization for Stability: The blend is supplied in a freeze-dried form, preserving the molecular structure against temperature fluctuations during transit

Modifications to increase resistance of the cells to stress Industrial production setups and the requirement for cultivation in bioreactors cause diverse stress factors on fungal strains, such as stirring stress, toxic products synthesized during the process, and oxidative conditions

10.1016/j.jep.2020.112731 285 ZhouY.HeL.ZhangN.MaL.YaoL