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) Summary and Conclusions Genetic variation in folate metabolism has emerged as a critical area of investigation, not only for its role in rare hereditary disorders but for its far-reaching implications in common, multifactorial conditions such as cardiovascular disease, birth defects, cancer, and neurodevelopmental disorders

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The expression profile of these gene in controls in GPL96 is similar to that of the NC group, whereas the gene expression profile of the PD individuals in GPL96 is similar to that of the ROT group (Fig