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International Multiple Sclerosis Genetics, C Genetics, Consortium, Beecham AH, Patsopoulos NA, Xifara DK, Davis MF et al

-TrCP is a substrate receptor for the S-phase kinase-associated protein 1 (Skp1)-Cul1-Rbx1/Roc1 ubiquitin ligase complex that targets Nrf2 for ubiquitination and proteasomal degradation (Chowdhry et al., 2013)

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