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The used methods included high-performance liquid chromatography coupled with mass spectrometry, Alamar Blue assay, real-time qPCR, and the Mito Stress Test of the Seahorse Analyzer (Agilent, Santa Clara, California, USA)

The products only share one active ingredient, though, and Vertex said the combination of drugs used in Alyftrek has benefits over Trikafta, which generated sales of $8.9 billion in 2023

Commonly Reported Mild Side Effects Injection site redness, swelling, or irritation Headache or lightheadedness Temporary fatigue, especially during the first week Mild gastrointestinal discomfort or nausea Occasional insomnia Less Common Reported Effects According to the U.S