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Abstract Drug-tolerant persister (DTP) cells are a subpopulation of cancer cells capable of surviving therapeutic stress through reversible, non-genetic adaptations

(D) Relative luciferase activity measured in HepG2-C3 cells transfected with pTXINV-XRE and incubated with 1, 10 or 100M skatole for 2, 4, 8 or 24 h, following 30 min pre-incubation with DMSO (control) or 3 M CH223191 (a specific AhR antagonist) (n = 3)

The company also donates 5% of profits to the Hawaii Fungi Project, a non-profit dedicated to studying and preserving the native Hawaiian mushrooms, some of which are already on the IUCNs Endangered Species list and have seldom been seen by human eyes

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