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Description

Erastin, one of the earliest discovered ferroptosis inducers, is a small molecule that inhibits the cysteine/glutamate antiporter system [36]

And yes, it supports the use of fatty acids to be burned as energy.(7)

Indeed, the conversion of a catalytic Cys thiol into a disulfide is a powerful means for shutting down enzymatic activity because disulfides are poor nucleophiles compared to thiolates