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PMID: 25296496

Das klinische Entwicklungsprogramm wurde jedoch nach schwerwiegenden unerwnschten Ereignissen unterbrochen, darunter ein Todesfall whrend einer klinischen Studie, obwohl der Kausalzusammenhang mit CJC-1295 nicht definitiv nachgewiesen wurde

Additionally, PRDX6 acts as a selenium-binding protein that promotes efficient intracellular selenium utilization, thereby sustaining GPX4 expression and activity and indirectly enhancing resistance to ferroptosis (Ito et al., 2024)