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The decision between these peptides and established regenerative medicine approaches should be based on available evidence, regulatory status, and individual patient factors

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Before cytokine stimulation, cultures were pre-treated for 1 h with 25 M 6-amino-1,4-dihydro-4-[5-(hydroxymethyl) (SHIN1), a serine hydroxymethyltransferase 1 and 2 (SHMT1/SHMT2) inhibitor (MedChemExpress, Monmouth Junction, NJ, USA), IUPAC name: 6-amino-1,4-dihydro-4-[5-(hydroxymethyl)[1,1'-biphenyl]-3-yl]-3-methyl-4-(1-methylethyl)pyrano[2,3-c]pyrazole-5-carbonitrile) [22]

10.1016/j.drudis.2021.12.018