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The light triggered splitting of water molecule in the oxygen-evolving complex (OEC) and subsequent transfer of e from photosystem II (PSII) to photosystem I (PSI) generates ROS in chloroplasts (Trubitsin et al., 2014)

In addition, conventional treatments such as radiation therapy and chemotherapeutic agents can promote ferroptosis, thereby increasing ferroptosis sensitivity and ultimately enhancing the efficacy of existing anticancer therapies 6,7

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