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The saturated fatty acids found in animal fats can indeed trigger a pro-inflammatory response through the activation of cytokine transcription

Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study

Previous research has demonstrated that xCT serves a crucial role in ferroptosis in certain cell types such as F98, 143B, BjeHLT, BJeLR, Calu-1 and HT-1080 cells (87,111)

Due to the localization of QSOX in the Golgi and secretory granules, its function may be to ensure disulfide integrity during late-stage maturation and secretion, as well as formation of larger complexes after secretion ( As a whole, oxidative foldingwhether forming or reducing disulfidesconstitutes a major burden for the cell, particularly in cell types with high secretory loads